Overview
- SupplierGeneTex
- Product NameSOX2 antibody [N1C3]
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.15 mg/ml
- IsotypeIgG
- Scientific DescriptionThis intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- A functional genomics approach to investigate the differentiation of iPSCs into lung epithelium at air-liquid interface. Kerschner JL et al., 2020 Sep, J Cell Mol MedRead more
- Activation of Sphingosine 1-Phosphate Receptor 1 Enhances Hippocampus Neurogenesis in a Rat Model of Traumatic Brain Injury: An Involvement of MEK/Erk Signaling Pathway. Ye Y et al., 2016, Neural PlastRead more
- ACTL6A interacts with p53 in acute promyelocytic leukemia cell lines to affect differentiation via the Sox2/Notch1 signaling pathway. Zhong PQ et al., 2019 Jan, Cell SignalRead more
- Antroquinonol, a Ubiquinone Derivative from the Mushroom Antrodia camphorata, Inhibits Colon Cancer Stem Cell-like Properties: Insights into the Molecular Mechanism and Inhibitory Targets. Lin HC et al., 2017 Jan 11, J Agric Food ChemRead more
- CCAAT/Enhancer-binding protein delta mediates glioma stem-like cell enrichment and ATP-binding cassette transporter ABCA1 activation for temozolomide resistance in glioblastoma. Wang SM et al., 2021 Jan 12, Cell Death DiscovRead more
- Cell Type- and Sex-Dependent Transcriptome Profiles of Rat Anterior Pituitary Cells. Fletcher PA et al., 2019, Front Endocrinol (Lausanne)Read more
- Characterisation of extraembryonic endoderm-like cells from mouse embryonic fibroblasts induced using chemicals alone. He X et al., 2020 Apr 16, Stem Cell Res TherRead more
- Compromised Chondrocyte Differentiation Capacity in TERC Knockout Mouse Embryonic Stem Cells Derived by Somatic Cell Nuclear Transfer. Chang WF et al., 2019 Mar 12, Int J Mol SciRead more
- Cops2 promotes pluripotency maintenance by Stabilizing Nanog Protein and Repressing Transcription. Zhang W et al., 2016 May 26, Sci RepRead more
- Cross Talk between One-Carbon Metabolism, Eph Signaling, and Histone Methylation Promotes Neural Stem Cell Differentiation. Fawal MA et al., 2018 Jun 5, Cell RepRead more