SUMO2/3 Antibody
ORB385842
Overview
- SupplierBiorbyt
- Product NameSUMO2/3 Antibody
- Delivery Days Customer16
- ApplicationsImmunoFluorescence
- Applications SupplierImmunofluorescence: 1-2ug/ml,Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1) IF, IHC-P, WB
- CertificationResearch Use Only
- Clone IDS23MT-1
- IsotypeIgG
- Scientific DescriptionThe small ubiquitin-related modifier (SUMO) proteins, which include SUMO1, 2 and 3, belong to the ubiquitin-like protein family. SUMO proteins are synthesized as precursors that undergo processing before conjugation to target proteins. Sumoylation targets for a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. SUMO2/3 contribute to a greater percentage of protein modification than does SUMO1 and they can form polymeric chains. In addition, SUMO3 regulates beta-Amyloid generation and may be critical in the onset or progression of Alzheimeri1/2s disease.
- UNSPSC12352203