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GTX103323 WB Image
GTX103323 WB Image
GTX103323 WB Image

T-Plastin antibody

Research Use Only
GTX103323
GeneTex
Product group Antibodies
Price on request
Packing Size
Large volume orders?
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Overview

  • Supplier
    GeneTex
  • Product Name
    T-Plastin antibody
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    0.23 mg/ml
  • Isotype
    IgG
  • Scientific Description
    Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). The C-terminal 570 amino acids of the T-plastin and L-plastin proteins are 83% identical. It contains a potential calcium-binding site near the N terminus. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Effect of genetic background on the phenotype of the Smn2B/- mouse model of spinal muscular atrophy. Eshraghi M et al., 2016 Oct 15, Hum Mol Genet
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  • PLS3 mutations in X-linked osteoporosis with fractures. van Dijk FS et al., 2013 Oct 17, N Engl J Med
    Read more