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ProductsBack/TET2 antibody [N2-2], N-term
GTX124205 ICC/IF Image
GTX124205 ICC/IF Image
GTX124205 ICC/IF Image

TET2 antibody [N2-2], N-term

Research Use Only
GTX124205
GeneTex
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Product group Antibodies
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More than 130 suppliers
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Overview

  • Supplier
    GeneTex
  • Product Name
    TET2 antibody [N2-2], N-term
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders. Two variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Changes in DNA 5-Hydroxymethylcytosine Levels and the Underlying Mechanism in Non-functioning Pituitary Adenomas. Xu Y et al., 2020, Front Endocrinol (Lausanne)
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  • DNA Demethylation by DNMT3A and DNMT3B in vitro and of Methylated Episomal DNA in Transiently Transfected Cells. Chatterjee B et al., 2018 Nov, Biochim Biophys Acta Gene Regul Mech
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  • Epigenetic underpinnings of freeze avoidance in the goldenrod gall moth, Epiblema scudderiana. Williamson SM et al., 2021 Oct, J Insect Physiol
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  • Genome-wide 5-Hydroxymethylcytosine Profiling Analysis Identifies MAP7D1 as A Novel Regulator of Lymph Node Metastasis in Breast Cancer. Wu SL et al., 2021 Feb, Genomics Proteomics Bioinformatics
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  • Ginsenoside 20(S)-Rg3 Inhibits the Warburg Effect Via Modulating DNMT3A/ MiR-532-3p/HK2 Pathway in Ovarian Cancer Cells. Zhou Y et al., 2018, Cell Physiol Biochem
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  • HDAC4 inhibition disrupts TET2 function in high-risk MDS and AML. Huang F et al., 2020 Jul 29, Aging (Albany NY)
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  • HDAC4 inhibition disrupts TET2 function in high-risk MDS and AML. Huang F et al., 2020 Jul 29, Aging (Albany NY)
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  • Hydrogen sulfide attenuates renal fibrosis by inducing TET-dependent DNA demethylation on Klotho promoter. Gu Y et al., 2020 Sep, FASEB J
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  • IGF2BP1 expression in human mesenchymal stem cells significantly affects their proliferation and is under the epigenetic control of TET1/2 demethylases. Mahaira LG et al., 2014 Oct 15, Stem Cells Dev
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  • Methyl-CpG Binding Domain Protein 2 Inhibits the Malignant Characteristic of Lung Adenocarcinoma through the Epigenetic Modulation of 10 to 11 Translocation 1 and miR-200s. Pei YF et al., 2019 May, Am J Pathol
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