GTX129604 IP Image
GTX129604 IP Image
Timeless antibody
GTX129604
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameTimeless antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1 mg/ml
- IsotypeIgG
- Scientific DescriptionRequired for normal progression of S-phase. Involved in the circadian rhythm autoregulatory loop. Negatively regulates CLOCK-NPAS2/BMAL1-induced transactivation of PER1 possibly via translocation of PER1 into the nucleus. Promotes TIPIN nuclear localiZation. Involved in cell survival after DNA damage or replication stress. May be specifically required for the ATR-CHK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light. May also play an important role in epithelial cell morphogenesis and formation of branching tubules.
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells. Truong LN et al., 2013 May 7, Proc Natl Acad Sci U S ARead more