TIMP1 antibody [C2C3], C-term
GTX108254
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameTIMP1 antibody [C2C3], C-term
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Impact of flavonoids on matrix metalloproteinase secretion and invadopodia formation in highly invasive A431-III cancer cells. Lin YC et al., 2013, PLoS OneRead more
- M3 receptor modulates extracellular matrix synthesis via ERK1/2 signaling pathway in human bladder smooth muscle cells. Chen S et al., 2020 Nov, J Cell BiochemRead more
- Profiling of selected angiogenesis-related genes in proliferative eutopic endometrium of women with endometriosis. Laudanski P et al., 2014 Jan, Eur J Obstet Gynecol Reprod BiolRead more
- Regulation of the regenerative activity of dental pulp stem cells from exfoliated deciduous teeth (SHED) of children by TGF-beta1 is associated with ALK5/Smad2, TAK1, p38 and MEK/ERK signaling. Chang HH et al., 2020 Nov 4, Aging (Albany NY)Read more