GTX127310 WB Image
GTX127310 WB Image
Twist1/2 antibody
GTX127310
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameTwist1/2 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.67 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes a basic helix-loop-helix (bHLH) transcription factor that plays an important role in embryonic development. The encoded protein forms both homodimers and heterodimers that bind to DNA E box sequences and regulate the transcription of genes involved in cranial suture closure during skull development. This protein may also regulate neural tube closure, limb development and brown fat metabolism. This gene is hypermethylated and overexpressed in multiple human cancers, and the encoded protein promotes tumor cell invasion and metastasis. Mutations in this gene cause Saethre-Chotzen syndrome in human patients, which is characterized by craniosynostosis, ptosis and hypertelorism. [provided by RefSeq, Aug 2017]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
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- Aqueous extract of Polygonum bistorta modulates proteostasis by ROS-induced ER stress in human hepatoma cells. Liu YH et al., 2017 Jan 30, Sci RepRead more
- Biological Landscape of Triple Negative Breast Cancers Expressing CTLA-4. Navarrete-Bernal MGC et al., 2020, Front OncolRead more
- Biomarker discovery in highly invasive lung cancer cell through proteomics approaches. Kuo CH et al., 2021 Apr, Cell Biochem FunctRead more
- Cathelicidin suppresses colon cancer development by inhibition of cancer associated fibroblasts. Cheng M et al., 2015, Clin Exp GastroenterolRead more
- Chaperonin-Containing TCP-1 Promotes Cancer Chemoresistance and Metastasis through the AKT-GSK3beta-beta-Catenin and XIAP-Survivin Pathways. Chang YX et al., 2020 Dec 21, Cancers (Basel)Read more