uPA antibody (FITC)
GTX79586
Overview
- SupplierGeneTex
- Product NameuPA antibody (FITC)
- Delivery Days Customer10
- ApplicationsELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration10 mg/ml
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimers disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203