GTX113294 IHC-P Image
GTX113294 IHC-P Image
Vinculin antibody [N1N3]
GTX113294
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameVinculin antibody [N1N3]
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.21 mg/ml
- IsotypeIgG
- Scientific DescriptionVinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
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- Gut epithelial and vascular barrier abnormalities in patients with chronic intestinal pseudo-obstruction. Boschetti E et al., 2019 Aug, Neurogastroenterol MotilRead more
- Multiplex profiling identifies clinically relevant signalling proteins in an isogenic prostate cancer model of radioresistance. Inder S et al., 2019 Nov 22, Sci RepRead more
- NDUFS3 depletion permits complex I maturation and reveals TMEM126A/OPA7 as an assembly factor binding the ND4-module intermediate. DAngelo L et al., 2021 Apr 20, Cell RepRead more
- Substrate stiffness regulates filopodial activities in lung cancer cells. Liou YR et al., 2014, PLoS OneRead more