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BAFF, Soluble (human) ELISA Kit (hypersensitive)

Research Use Only
AG-45B-0001
AdipoGen Life Sciences
ReactivityHuman
Product group Assays
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    BAFF, Soluble (human) ELISA Kit (hypersensitive)
  • Delivery Days Customer
    10
  • Applications
    ELISA
  • Assay Detection Range
    15.6 - 500 pg/ml
  • Assay Sensitivity
    8pg/ml
  • Assay Specificity
    Detects human BAFF. Does not detect mouse BAFF.
  • Certification
    Research Use Only
  • Scientific Description
    BAFF (B cell-activating factor; BLyS; B lymphocyte stimulator; TNFSF13B; TALL-1; CD257), belonging to the TNF family, is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation. BAFF co-stimulates activated T cells. Increased levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases, such as Sjoegrens syndrome, rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus (SLE). Furthermore, BAFF is found in inflammatory sites in which there is lymphoid neogenesis. BAFF levels are elevated in patients with multiple myeloma and B cell chronic lymphoid leukemia (B-CCL). - ELISA Assay. Detects human BAFF. Does not detect mouse BAFF. Colorimetric assay. Sample Types: Cell Culture Supernatant, Plasma, Serum. Range: 15.6 - 500 pg/ml. Sensitivity: 8pg/ml. BAFF (B cell-activating factor; BLyS; B lymphocyte stimulator; TNFSF13B; TALL-1; CD257), belonging to the TNF family, is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation. BAFF co-stimulates activated T cells. Increased levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases, such as Sjoegrens syndrome, rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus (SLE). Furthermore, BAFF is found in inflammatory sites in which there is lymphoid neogenesis. BAFF levels are elevated in patients with multiple myeloma and B cell chronic lymphoid leukemia (B-CCL).
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    41116133