Caspase-1 (mouse) ELISA Kit

Catalog number: AG-45B-0002-KI01
Brand: AdipoGen Life Sciences
Packing: 1 x 96 well plate
Price: € 540.00
Expected delivery time: 7 days
Quantity:

Product specifications for - Caspase-1 (mouse) ELISA Kit

Overview: 
Product group: Assays
Category: ELISA / EIA
Application: ELISA
Species: Mouse
Target: Casp1
Target description: caspase 1
Properties: 
Assay Sensitivity: 33pg/ml
Assay Detection Range: 0.15ng/ml to 10ng/ml
Datasheet: Datasheet
  Research Use Only
UNSPSC: 41116158
Scientific information: 
Scientific info: Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and interleukin-18 (IL-18) and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3/NALP3 responds to a variety of agonists including crystals. This Caspase-1 (mouse) ELISA Kit can be used to measure caspase-1 (mouse) in cell culture supernatants, serum and plasma. It is a quantitative detection method, alternative to Western blotting to measure caspase-1 secretion. - ELISA Assay. Detects mouse caspase-1 (proform as well as p10 and p20 domain). Does not detect human caspase-1. Colorimetric assay. Sample Types: Cell Culture Supernatant, Plasma, Serum. Range: 0.15ng/ml to 10ng/ml. Sensitivity: 33pg/ml. Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and interleukin-18 (IL-18) and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3/NALP3 responds to a variety of agonists including crystals. This Caspase-1 (mouse) ELISA Kit can be used to measure caspase-1 (mouse) in cell culture supernatants, serum and plasma. It is a quantitative detection method, alternative to Western blotting to measure caspase-1 secretion.
Gene ID: 12362
Swiss prot ID: P29452
Safety information: 
MSDS: MSDS
Additional information: 
Synonyms: CASP-1; caspase-1; ICE; IL-1 beta-converting enzyme; IL-1B converting enzyme; Il1bc; IL-1BC; interleukin-1 beta convertase; interleukin-1 beta-converting enzyme; p45
Pharmacologic inhibition of IkappaB kinase activates immediate hypersensitivity reactions in mice: D. Miyazaki, et al.; Am. J. Pathol. 183, 96 (2013) Read more