Rat IL1 beta ELISA Kit

Arigo Biolaboratories

Rat IL1 beta ELISA Kit

23

ELISA

CV:

30 pg/ml

No significant cross-reactivity or interference with Human IL-2,4,1 alpha,sIL-2R,sIL-4R; mouse IL-2,4,10,1 alpha; rat GM-CSF, IL-2,4,10,1 alpha, SCF, TNF- alpha

4 hours

Research Use Only

IL1 beta protein is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]

2°C to 8°C

41116133