(+)-JQ1 [1268524-70-4]
S7110
Overview
- SupplierSelleck Chemicals
- Product Name(+)-JQ1 [1268524-70-4]
- Delivery Days Customer9
- CAS Number1268524-70-4
- CertificationResearch Use Only
- Scientific Description(+)-JQ1 is a BET bromodomain inhibitor, with IC50 of 77 nM/33 nM for BRD4(1/2) in cell-free assays, binding to all bromodomains of the BET family, but not to bromodomains outside the BET family. (+)-JQ1 suppresses cell proliferation via inducing autophagy. (+)-JQ1 inhibits the expression of Nuclear receptor binding SET domain protein 3 (NSD3) target genes.
- UNSPSC12352200