Afatinib [439081-18-2]
27009
CAS Number439081-18-2
Product group Chemicals
Estimated Purity≥95% by HPLC.
Molecular Weight485.9 Da
Overview
- SupplierBPS Bioscience
- Product NameAfatinib [439081-18-2]
- Delivery Days Customer7
- CAS Number439081-18-2
- CertificationResearch Use Only
- Estimated Purity≥95% by HPLC.
- Molecular FormulaC24H25ClFN5O3
- Molecular Weight485.9 Da
- Scientific DescriptionAfatinib, also known as BIW-2992, is an irreversible dual inhibitor of epidermal growth factor receptor 1 (EGFR) and 2 (HER2) tyrosine kinases. Afatinib suppresses EGF-induced EGFR phosphorylation and cellular proliferation in various cell lines, including EGFR-overexpressing and HER2-expressing cell lines A431, NIH-3T3-HER2, NCI-N87 and BT-474.
- Storage Instruction-20°C
- UNSPSC12352200