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ProductsBack/alpha-NETA [31059-54-8]
Chemical Structure
Chemical Structure
Chemical Structure

alpha-NETA [31059-54-8]

Research Use Only
AG-CR1-0151
AdipoGen Life Sciences
CAS Number31059-54-8
DownloadDatasheet
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Product group Chemicals
Estimated Purity>97% (NMR)
Molecular Weight369.2
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    alpha-NETA [31059-54-8]
  • Delivery Days Customer
    10
  • CAS Number
    31059-54-8
  • Certification
    Research Use Only
  • Estimated Purity
    >97% (NMR)
  • Hazard Information
    Non-hazardous,Warning
  • Molecular Formula
    C16H20INO
  • Molecular Weight
    369.2
  • Scientific Description
    Chemical. CAS: 31059-54-8. Formula: C16H20INO. MW: 369.2. Potent fluorescent inhibitor of choline acetyltransferase. CMKLR1 antagonist. Inhibits chemerin-stimulated beta-arrestin2 association with CMKLR1, as well as chemerin-triggered CMKLR1+ cell migration. Aldehyde dehydrogenase 1 (ALDH1A1) antagonist. - Potent fluorescent inhibitor of choline acetyltransferase. CMKLR1 antagonist. Inhibits chemerin-stimulated beta-arrestin2 association with CMKLR1, as well as chemerin-triggered CMKLR1+ cell migration. Aldehyde dehydrogenase 1 (ALDH1A1) antagonist.
  • SMILES
    [I-].C[N+](C)(C)CCC(=O)C1=C2C=CC=CC2=CC=C1
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352200

References

  • 2-(alpha-Naphthoyl)ethyltrimethylammonium iodide and its beta-isomer: new selective, stable and fluorescent inhibitors of choline acetyltransferase: B.V. Sastry, et al.; J. Pharmacol. Exp. Ther. 245, 72 (1988)
  • Relationships between chemical structure and inhibition of choline acetyltransferase by 2-(alpha-naphthoyl)ethyl trimethylammonium and related compounds: B.V. Sastry, et al.; Pharmacol. Res. Commun. 20, 751 (1988)
  • Regulation of the choline transport system in superfused microcarrier cultures of BeWo cells: B.M Eaton & S.R. Sooranna; Placenta 19, 663 (1998)
  • Eosinophil-induced release of acetylcholine from differentiated cholinergic nerve cells: D.A. Sawatzky, et al.; Am. J. Physiol. Lung Cell Mol. Physiol. 285, L1296 (2003)
  • A novel CMKLR1 small molecule antagonist suppresses CNS autoimmune inflammatory disease: K.L. Graham, et al.; PLoS One 9, e112925 (2014)