Navtemadlin [1352066-68-2]
HY-12296
CAS Number1352066-68-2
Product group Chemicals
Estimated Purity96.04%
Molecular Weight568.55
Overview
- SupplierMedChem Express
- Product NameNavtemadlin [1352066-68-2]
- Delivery Days Customer10
- CAS Number1352066-68-2
- CertificationResearch Use Only
- Estimated Purity96.04%
- Molecular FormulaC28H35Cl2NO5S
- Molecular Weight568.55
- Scientific DescriptionNavtemadlin (AMG 232) is a potent, selective and orally available inhibitor of p53-MDM2 interaction, with an IC50 of 0.6 nM. Navtemadlin binds to MDM2 with a Kd of 0.045 nM.
- SMILESO=C(O)C[C@]1(C)C(N([C@H](CS(=O)(C(C)C)=O)C(C)C)[C@H](C2=CC=C(Cl)C=C2)[C@@H](C3=CC=CC(Cl)=C3)C1)=O
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352200