Aprepitant (MK-0869) [170729-80-3]

Selleck Chemicals

Aprepitant (MK-0869) [170729-80-3]

9

170729-80-3

Research Use Only

Aprepitant (MK-0869, L-754030) is a potent and selective neurokinin-1 receptor antagonist with IC50 of 0.1 nM. Aprepitant reduces levels of pro-inflammatory cytokines including G-CSF, IL-6, IL-8 and TNFalfa. Aprepitant inhibits HIV infection of human macrophages.

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