Aurothioglucose [12192-57-3]

MedChem Express

Aurothioglucose [12192-57-3]

10

12192-57-3

Research Use Only

C6H11AuO5S

392.18

Aurothioglucose (Gold thioglucose), containing monovalent gold ion, is a potent active-site inhibitor of TrxR1 (thioredoxin reductase 1), with an IC50 of 65 nM. Aurothioglucose inhibits the DNA binding of NF-kappaB in vitro. Aurothioglucose shows anti-HIV and anti-rheumatic activities.

O[C@@H]1[C@](O[Au+][SH-]2)([H])C2O[C@H](CO)[C@H]1O

2°C to 8°C,-20°C,-80°C

12352200