Autophinib [1644443-47-9]
HY-101920
CAS Number1644443-47-9
Product group Chemicals
Estimated Purity99.56%
Molecular Weight346.73
Overview
- SupplierMedChem Express
- Product NameAutophinib [1644443-47-9]
- Delivery Days Customer10
- CAS Number1644443-47-9
- Estimated Purity99.56%
- Molecular FormulaC14H11ClN6O3
- Molecular Weight346.73
- Scientific DescriptionAutophinib is a potent, selective autophagy inhibitor with IC50s of 90 nM and 40 nM for starvation- and Rapamycin-induced autophagy, respectively. Autophinib is also an ATP competitive Vacuolar Protein Sorting 34 (VPS34) inhibitor with an IC50 of 19 nM. Autophinib inhibits autophagy induced by starvation or Rapamycin by targeting VPS34.
- SMILESCC1=CC(NC2=NC(OC3=CC=C([N+]([O-])=O)C=C3)=NC(Cl)=C2)=NN1
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200