Azoramide [932986-18-0]
HY-18705
Overview
- SupplierMedChem Express
- Product NameAzoramide [932986-18-0]
- Delivery Days Customer10
- CAS Number932986-18-0
- CertificationResearch Use Only
- Molecular FormulaC15H17ClN2OS
- Molecular Weight308.83
- Scientific DescriptionAzoramide is a potent, orally active small-molecule modulator of the unfolded protein response (UPR). Azoramide improves ER protein folding and elevates ER chaperone capacity, which together protects cells against ER stress. Azoramide alleviates PLA2G6 mutant-induced ER stress through modulating unfolded protein response, and enhances the CERB signaling to rescue mitochondrial function, thereby preventing apoptosis of DA neurons. Azoramide has antidiabetic activity.
- SMILESCCCC(NCCC1=CSC(C2=CC=C(Cl)C=C2)=N1)=O
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200