BAY 11-7082 [19542-67-7]
HY-13453
Overview
- SupplierMedChem Express
- Product NameBAY 11-7082 [19542-67-7]
- Delivery Days Customer10
- CAS Number19542-67-7
- CertificationResearch Use Only
- Estimated Purity98.91%
- Molecular FormulaC10H9NO2S
- Molecular Weight207.25
- Scientific DescriptionBAY 11-7082 is an IkappaBalpha phosphorylation and NF-kappaB inhibitor. BAY 11-7082 selectively and irreversibly inhibits the TNF-alpha-induced phosphorylation of IkappaB-alpha, and decreases NF-kappaB and expression of adhesion molecules. BAY 11-7082 inhibits ubiquitin-specific protease USP7 and USP21 (IC50=0.19, 0.96 microM, respectively). BAY 11-7082 inhibits gasdermin D (GSDMD) pore formation in liposomes and inflammasome-mediated pyroptosis and IL-1beta secretion in human and mouse cells.
- SMILESN#C/C=C/S(=O)(C1=CC=C(C)C=C1)=O
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200