Bromosporine [1619994-69-2]
HY-15815
CAS Number1619994-69-2
Product group Chemicals
Estimated Purity99.6%
Molecular Weight404.44
Overview
- SupplierMedChem Express
- Product NameBromosporine [1619994-69-2]
- Delivery Days Customer10
- CAS Number1619994-69-2
- CertificationResearch Use Only
- Estimated Purity99.6%
- Molecular FormulaC17H20N6O4S
- Molecular Weight404.44
- Scientific DescriptionBromosporine is a potent BET inhibitor with an IC50 value of 2.1 microM for PCAF. Bromosporine can arrest cell cycle and induce apoptosis in cancer cells. Bromosporine exhibits excellent antitumor activity in xenograft mice model when combined with 5-FU (HY-90006). Bromosporine can increase CDK9 T-loop phosphorylation in HIV-1 latency models, resulting the protection of reactivate HIV-1 replication from latency. Bromosporine can be used to research colorectal cancer, acute myeloid leukemia (AML) and AIDS.
- SMILESO=C(OCC)NC1=CC(C2=CC=C(C)C(NS(=O)(C)=O)=C2)=NN3C1=NN=C3C
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200