Closantel [57808-65-8]

MedChem Express

Closantel [57808-65-8]

10

57808-65-8

Research Use Only

98%

C22H14Cl2I2N2O2

663.07

Closantel is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC50 of 1.6 microM and a Ki of 468 nM. Closantel inhibits the O. volvulus L3 to L4 molt of developing.

O=C(NC1=CC(Cl)=C(C(C2=CC=C(Cl)C=C2)C#N)C=C1C)C3=CC(I)=CC(I)=C3O

2°C to 8°C,-20°C,-80°C

12352200