Dabigatran [211914-51-1]

MedChem Express

Dabigatran [211914-51-1]

10

211914-51-1

96.84%

C25H25N7O3

471.51

Dabigatran (BIBR 953), an oral anticoagulant, is a reversible, potent, competitive direct thrombin inhibitor (Ki=4.5 nM). Dabigatran (BIBR 953) also inhibits thrombin-induced platelet aggregation (IC50=10 nM).

N=C(N)C(C=C1)=CC=C1NCC2=NC3=CC(C(N(CCC(O)=O)C4=NC=CC=C4)=O)=CC=C3N2C

2°C to 8°C,-20°C,-80°C

12352200