Daclatasvir dihydrochloride [1009119-65-6]

MedChem Express

Daclatasvir dihydrochloride [1009119-65-6]

10

1009119-65-6

Research Use Only

95%

C40H52Cl2N8O6

811.8

Daclatasvir dihydrochloride (BMS-790052 dihydrochloride) is a potent and orally active HCV NS5A protein inhibitor with EC50s range of 9-146 pM for multiple HCV replicon genotypes. Daclatasvir dihydrochloride is also an organic anion transporting polypeptide 1B (OATP1B) and OATP1B3 inhibitor with IC50s of 1.5 microM and 3.27 microM, respectively.

O=C(N1CCC[C@H]1C2=NC=C(C3=CC=C(C4=CC=C(C=C4)C5=CN=C(N5)[C@@H]6CCCN6C([C@H](C(C)C)NC(OC)=O)=O)C=C3)N2)[C@H](C(C)C)NC(OC)=O.[H]Cl.[H]Cl

2°C to 8°C,-20°C,-80°C

12352200