Danoprevir [850876-88-9]
HY-10238
CAS Number850876-88-9
Product group Chemicals
Estimated Purity95.65%
Molecular Weight731.83
Overview
- SupplierMedChem Express
- Product NameDanoprevir [850876-88-9]
- Delivery Days Customer10
- CAS Number850876-88-9
- CertificationResearch Use Only
- Estimated Purity95.65%
- Molecular FormulaC35H46FN5O9S
- Molecular Weight731.83
- Scientific DescriptionDanoprevir (ITMN-191) is an orally active NS3/4A protease inhibitor for hepatitis C virus (HCV) with an IC50 of 0.29 nM and is selective for NS3/4A over a panel of 53 proteases (IC50 higher than 10 microM). Danoprevir (ITMN-191) inhibits HCV genotypes 1a, 1b, 4, 5, and 6 (IC50s=0.2-0.4 nM) as well as 2b and 3a (IC50s=1.6, 3.5 nM). Danoprevir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 0.05 microM.
- SMILESO=S(NC([C@@]1(NC([C@]2([H])C[C@@H](OC(N3CC4=C(C3)C=CC=C4F)=O)CN2C5=O)=O)C[C@]1(/C=C/CCCCC[C@@H]5NC(OC(C)(C)C)=O)[H])=O)(C6CC6)=O
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200