Stenoparib (E7449) [1140964-99-3]
S8419
Overview
- SupplierSelleck Chemicals
- Product NameStenoparib (E7449) [1140964-99-3]
- Delivery Days Customer9
- CAS Number1140964-99-3
- CertificationResearch Use Only
- Scientific DescriptionStenoparib (E7449) is an orally bioavailable, brain penetrable, small molecule dual inhibitor of PARP1/2 and also inhibits PARP5a/5b, otherwise known as tankyrase1 and 2 (TNKS1/2), important regulators of canonical Wnt/bèta-catenin signaling. It has IC50 values of 1.0 and 1.2 nM for PARP1 and 2, respectively.
- UNSPSC12352200