EG00229 [1210945-69-9]

MedChem Express

EG00229 [1210945-69-9]

10

1210945-69-9

Research Use Only

98.01%

C19H20F3N7O7S3

611.6

EG00229 is a neuropilin 1 (NRP1) receptor antagonist. EG00229 selectively inhibits VEGF-A binding to NRP1 b1 domain with an IC50 of 3 microM, but has no effect on VEGFA binding to VEGFR-1 and VEGFR-2.

N=C(N)NCCC[C@@H](C(O)=O)NC(C1=C(NS(=O)(C2=CC=CC3=NSN=C32)=O)C=CS1)=O.O=C(O)C(F)(F)F

2°C to 8°C,-20°C,-80°C

12352200