Entacapone [130929-57-6]
HY-14280
CAS Number130929-57-6
Product group Chemicals
Estimated Purity98.79%
Molecular Weight305.29
Overview
- SupplierMedChem Express
- Product NameEntacapone [130929-57-6]
- Delivery Days Customer10
- CAS Number130929-57-6
- CertificationResearch Use Only
- Estimated Purity98.79%
- Molecular FormulaC14H15N3O5
- Molecular Weight305.29
- Scientific DescriptionEntacapone is a potent, reversible, peripherally acting and orally active catechol-O-methyltransferase (COMT) inhibitor. Entacapone inhibits COMT from rat brain, erythrocytes and liver with IC50 values of 10 nM, 20 nM, and 160 nM, respectively. Entacapone is selective for COMT over other catecholamine metabolizing enzymes, including MAO-A, MAO-B, phenolsulphotransferase M (PST-M) and PST-P (IC50s>50 microM). Entacapone can be used for the research of Parkinsons disease. Entacapone serves as a inhibitor of FTO demethylation with an IC50 of 3.5 microM, can be used for the research of metabolic disorders.
- SMILESO=C(N(CC)CC)/C(C#N)=C/C1=CC([N+]([O-])=O)=C(O)C(O)=C1
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200