Foretinib (GSK1363089) [849217-64-7]
S1111
Product group Chemicals
Overview
- SupplierSelleck Chemicals
- Product NameForetinib (GSK1363089) [849217-64-7]
- Delivery Days Customer9
- CertificationResearch Use Only
- Scientific DescriptionForetinib (GSK1363089, EXEL-2880, XL-880, GSK089) is an ATP-competitive inhibitor of HGFR and VEGFR, mostly for Met (c-Met) and KDR with IC50 of 0.4 nM and 0.9 nM in cell-free assays. Less potent against Ron, Flt-1/3/4, Kit (c-Kit), PDGFRalfa/bèta and Tie-2, and little activity to FGFR1 and EGFR. Phase 2.
- UNSPSC12352200