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Forodesine hydrochloride [284490-13-7]

HY-16209
MedChem Express
CAS Number284490-13-7
Product group Chemicals
Estimated Purity98.35%
Molecular Weight302.71
Price on request
Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Forodesine hydrochloride [284490-13-7]
  • Delivery Days Customer
    10
  • CAS Number
    284490-13-7
  • Estimated Purity
    98.35%
  • Molecular Formula
    C11H15ClN4O4
  • Molecular Weight
    302.71
  • Scientific Description
    Forodesine hydrochloride (BCX-1777 hydrochloride) is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50 values ranging from 0.48 to 1.57 nM for human, mouse, rat, monkey and dog PNP. Forodesine hydrochloride is a potent human lymphocyte proliferation inhibitor. Forodesine hydrochloride could induce apoptosis in leukemic cells by increasing the dGTP levels.
  • SMILES
    O=C1C(NC=C2[C@@H]3N[C@H](CO)[C@@H](O)[C@H]3O)=C2NC=N1.Cl
  • Storage Instruction
    -20°C,-80°C
  • UNSPSC
    12352200