GDC-0152 [873652-48-3]

MedChem Express

GDC-0152 [873652-48-3]

10

873652-48-3

Research Use Only

99.23%

C25H34N6O3S

498.64

GDC-0152 is a potent IAPs inhibitor, and binds to the BIR3 domains of XIAP, cIAP1, cIAP2 and the BIR domain of ML-IAP with Ki values of 28 nM, 17 nM, 43 nM and 14 nM, respectively.

O=C(N1[C@H](C(NC2=C(C3=CC=CC=C3)N=NS2)=O)CCC1)[C@H](C4CCCCC4)NC([C@H](C)NC)=O

2°C to 8°C,-20°C,-80°C

12352200