Ginsenoside Rb1 [41753-43-9]

Selleck Chemicals

Ginsenoside Rb1 [41753-43-9]

9

41753-43-9

Research Use Only

Ginsenoside Rb1 (Gypenoside Ⅲ) is a protopanaxadiol that has diverse in vitro and in vivo effects, including neuroprotective, anti-inflammatory, and anti-obesity actions. Ginsenoside Rb1, a main constituent of the root of Panax ginseng, inhibits Na+, K+-ATPase activity with IC50 of 6.3±1.0 muM. Ginsenoside also inhibits IRAK-1 activation and phosphorylation of NF-kappaB p65. Ginsenoside Rb1 reduces the expressions of TLR3, TLR4 and TRAF-6, and down-regulates the levels of TNF-alfa, IFN-bèta and iNOS.

12352200