GSK2194069 [1332331-08-4]
HY-12325
CAS Number1332331-08-4
Product group Chemicals
Estimated Purity99.67%
Molecular Weight428.48
Overview
- SupplierMedChem Express
- Product NameGSK2194069 [1332331-08-4]
- Delivery Days Customer10
- CAS Number1332331-08-4
- CertificationResearch Use Only
- Estimated Purity99.67%
- Molecular FormulaC25H24N4O3
- Molecular Weight428.48
- Scientific DescriptionGSK2194069 is a potent inhibitor of beta-ketoyl reductase (KR) of fatty acid synthase (FASN), with an IC50 value of 7.7 nM. GSK2194069 shows specifically inhibitory effect on FAS expressing cancer cells, by acting potent efficacy on acetoacetyl-CoA, NADPH with IC50 or Ki values of 4.8 nM and 5.6 nM, respectively.
- SMILESO=C(N1C[C@H](CC2=NNC(N2C3=CC=C(C4=CC=C(OC=C5)C5=C4)C=C3)=O)CC1)C6CC6
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200