INCB3344 [1262238-11-8]

MedChem Express

INCB3344 [1262238-11-8]

10

1262238-11-8

Research Use Only

96.59%

C29H34F3N3O6

577.59

INCB3344 is a potent, selective and orally bioavailable CCR2 antagonist with IC50 values of 5.1 nM (hCCR2) and 9.5 nM (mCCR2) in binding antagonism and 3.8 nM (hCCR2) and 7.8 nM (mCCR2) in antagonism of chemotaxis activity.

CCO[C@H]1CN([C@]2([H])CC[C@@](CC2)(C3=CC4=C(OCO4)C=C3)O)C[C@@H]1NC(CNC(C5=CC(C(F)(F)F)=CC=C5)=O)=O

2°C to 8°C,-20°C,-80°C

12352200