K-Ras ligand-Linker Conjugate 3 [2378261-87-9]

MedChem Express

K-Ras ligand-Linker Conjugate 3 [2378261-87-9]

10

Research Use Only

K-Ras ligand-Linker Conjugate 3 (Compound 001371) incorporates a ligand for K-Ras recruiting moiety, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). K-Ras ligand-Linker Conjugate 3 can be used in the synthesis of PROTAC K-Ras Degrader-1 (HY-129523), which is potent PROTAC K-Ras degrader that exhibits ≥70% degradation efficacy in SW1573 cells.

-20°C,-80°C

41116133