Laquinimod [248281-84-7]

MedChem Express

Laquinimod [248281-84-7]

10

248281-84-7

Research Use Only

99.36%

C19H17ClN2O3

356.8

Laquinimod (ABR-215062), an orally available carboxamide derivative, is a potent immunomodulator which prevents neurodegeneration and inflammation in the central nervous system. Laquinimod reduces astrocytic NF-kappaB activation to protect from Cuprizone-induced demyelination. Laquinimod has the potential for relapsing remitting (RR) and chronic progressive (CP) forms of multiple sclerosis (MS; RRMS or CPMS) as well as neurodegenerative diseases research.

O=C(C1=C(O)C2=C(N(C)C1=O)C=CC=C2Cl)N(CC)C3=CC=CC=C3

2°C to 8°C,-20°C,-80°C

12352200