Linezolid [165800-03-3]

Chemodex

Linezolid [165800-03-3]

10

165800-03-3

Research Use Only

>98%

Danger,Non-hazardous

C16H20FN3O4

337.35

Chemical. CAS: 165800-03-3. Formula: C16H20FN3O4. MW: 337.35. Synthetic. Linezolid is a synthetic oxazolidinone antibiotic with activity against a wide range of Gram-positive bacteria. Displays potent antibacterial activity against a variety of multidrug-resistant gram-positive microbes in vitro and in vivo, including resistant strains of several species, such as methicillin-resistant S. aureus (MRSA), penicillin-resistant pneumococci, vancomycin-resistant enterococci, various anaerobic bacteria, and several mycobacteria and streptococci (MICs = 2-4mg/ml). Linezolid inhibits protein synthesis by binding to domain V of the 23S ribosomal RNA of the 50S subunit of bacterial ribosomes and preventing the formation of a functional 70S initiation complex, thus inhibiting bacterial mRNA translation. Linezolid is also a weak, reversible, nonselective inhibitor of monoamine oxidase. - Linezolid is a synthetic oxazolidinone antibiotic with activity against a wide range of Gram-positive bacteria. Displays potent antibacterial activity against a variety of multidrug-resistant gram-positive microbes in vitro and in vivo, including resistant strains of several species, such as methicillin-resistant S. aureus (MRSA), penicillin-resistant pneumococci, vancomycin-resistant enterococci, various anaerobic bacteria, and several mycobacteria and streptococci (MICs = 2-4mg/ml). Linezolid inhibits protein synthesis by binding to domain V of the 23S ribosomal RNA of the 50S subunit of bacterial ribosomes and preventing the formation of a functional 70S initiation complex, thus inhibiting bacterial mRNA translation. Linezolid is also a weak, reversible, nonselective inhibitor of monoamine oxidase.

CC(NC[C@H]1CN(C2=CC=C(N3CCOCC3)C(F)=C2)C(O1)=O)=O

-20°C

12352200