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ProductsBack/M-110 [1395048-49-3]

M-110 [1395048-49-3]

Research Use Only
HY-12830
MedChem Express
CAS Number1395048-49-3
DownloadMSDS
Product group Chemicals
Estimated Purity95.27%
Molecular Weight445.94
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Overview

  • Supplier
    MedChem Express
  • Product Name
    M-110 [1395048-49-3]
  • Delivery Days Customer
    10
  • CAS Number
    1395048-49-3
  • Certification
    Research Use Only
  • Estimated Purity
    95.27%
  • Molecular Formula
    C22H28ClN5O3
  • Molecular Weight
    445.94
  • Scientific Description
    M-110 is a highly selective, ATP-competitive inhibitor of PIM kinases with a preference for PIM-3 (IC50=47 nM). M-110 inhibits PIM-1 and PIM-2 with similar IC50s of 2.5 microM. M-110 inhibits the proliferation of prostate cancer cell lines with IC50s of 0.6 to 0.9 microM.
  • SMILES
    O=C(N/N=C(C1=CC=C(Cl)C=C1O)\CC)C2=CC(NCCCN3CCOCC3)=NC=C2
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200