Masitinib [790299-79-5]
HY-10209
Overview
- SupplierMedChem Express
- Product NameMasitinib [790299-79-5]
- Delivery Days Customer10
- CAS Number790299-79-5
- CertificationResearch Use Only
- Estimated Purity95%
- Molecular FormulaC28H30N6OS
- Molecular Weight498.64
- Scientific DescriptionMasitinib (AB1010) is a potent, orally bioavailable, and selective inhibitor of c-Kit (IC50=200 nM for human recombinant c-Kit). It also inhibits PDGFRalpha/beta (IC50s=540/800 nM), Lyn (IC50= 510 nM for LynB), Lck, and, to a lesser extent, FGFR3 and FAK. Masitinib (AB1010) has anti-proliferative, pro-apoptotic activity and low toxicity.
- SMILESO=C(NC1=CC=C(C(NC2=NC(C3=CC=CN=C3)=CS2)=C1)C)C4=CC=C(CN5CCN(CC5)C)C=C4
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200