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ProductsBack/Melanin Production Inhibitor A3B5 [346721-60-6]
Chemical Structure
Chemical Structure
Chemical Structure

Melanin Production Inhibitor A3B5 [346721-60-6]

Research Use Only
AG-CR1-3605
AdipoGen Life Sciences
Estimated Purity>98% (NMR)
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Product group Chemicals
Molecular Weight255.3
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Melanin Production Inhibitor A3B5 [346721-60-6]
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Estimated Purity
    >98% (NMR)
  • Hazard Information
    Non-hazardous,Warning
  • Molecular Formula
    C16H17NO2
  • Molecular Weight
    255.3
  • Scientific Description
    Chemical. CAS: 346721-60-6. Formula: C16H17NO2. MW: 255.3. Non-cytotoxic melanogenesis inhibitor. Potential depigmentation agent. Tyrosinase-related protein 2 (TRP-2) expression inhibitor, via proteasomal degradation. Inhibits the proliferation of melanocytes and melanoma cells through cell cycle arrest in G1. Moderate skin tumor growth suppressor in vivo. - Non-cytotoxic melanogenesis inhibitor. Potential depigmentation agent. Tyrosinase-related protein 2 (TRP-2) expression inhibitor, via proteasomal degradation. Inhibits the proliferation of melanocytes and melanoma cells through cell cycle arrest in G1. Moderate skin tumor growth suppressor in vivo.
  • SMILES
    COC1=CC(=CC=C1)C(=O)NC1=CC(C)=CC(C)=C1
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352200

References

  • Identification of a potent and noncytotoxic inhibitor of melanin production: S. Hwang, et al.; Bioorg. Med. Chem. 18, 5602 (2010)
  • N-(3,5-dimethylphenyl)-3-methoxybenzamide (A(3)B(5)) targets TRP-2 and inhibits melanogenesis and melanoma growth: E.J. Lee, et al.; J. Invest. Dermatol. 131, 1701 (2011)