Mifepristone (RU486) [84371-65-3]
S2606
Overview
- SupplierSelleck Chemicals
- Product NameMifepristone (RU486) [84371-65-3]
- Delivery Days Customer9
- CAS Number84371-65-3
- CertificationResearch Use Only
- Scientific DescriptionMifepristone (RU486, C-1073, RU 38486, Mifegyne) is a remarkably active antagonist of progesterone receptor and glucocorticoid receptor with IC50 of 0.2 nM and 2.6 nM, respectively. Mifepristone promotes cell autophagy and apoptosis, decreases Bcl-2 level and increases Beclin1 level, accompanied by weakened interaction between Bcl-2 and Beclin1.
- UNSPSC12352200