Mitotane [53-19-0]
HY-13690
Overview
- SupplierMedChem Express
- Product NameMitotane [53-19-0]
- Delivery Days Customer10
- CAS Number53-19-0
- CertificationResearch Use Only
- Estimated Purity99.73%
- Molecular FormulaC14H10Cl4
- Molecular Weight320.04
- Scientific DescriptionMitotane (2,4-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions.
- SMILESClC1=CC=C(C(C2=CC=CC=C2Cl)C(Cl)Cl)C=C1
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200