MK-2894 sodium salt [1006036-88-9]

MedChem Express

MK-2894 sodium salt [1006036-88-9]

10

1006036-88-9

98.94%

C25H21F3NNaO3S

495.49

MK-2894 sodium salt is a potent, selective, orally active and high affinity (Ki=0.56 nM) full antagonist against E prostanoid receptor 4 (EP4 receptor) (IC50=2.5 nM). MK-2894 sodium salt possesses potent anti-inflammatory activity in animal models of pain/inflammation and can be used for the research of arthritis.

O=C(O[Na])C1=CC=C(C2(NC(C3=C(C)SC(C)=C3CC4=CC=C(C(F)(F)F)C=C4)=O)CC2)C=C1

2°C to 8°C,-20°C,-80°C

12352200