Monosodium urate (ready-to-use) [1198-77-2]

Catalog number: AG-CR1-3951-M010
Brand: AdipoGen Life Sciences
Packing: 10 mg
Price: € 380.00
Expected delivery time: 7 days
Quantity:
Chemical Structure
Chemical Structure...

Product specifications for - Monosodium urate (ready-to-use) [1198-77-2]

Overview: 
Product group: Chemicals
Category: Other
CAS No.: 1198-77-2
Properties: 
Molecular Formula: C5H3N4O3 . Na
Molecular weight: 167.1 . 23.0
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352200
Concentration: 20 mg/ml
Form supplied: In PBS.
Storage instructions: -20°C
Scientific information: 
Scientific info: Chemical. CAS: 1198-77-2. Formula: C5H3N4O3 . Na. MW: 167.1 . 23.0. NLRP3/NALP3 inflammasome activator. Specially crystallized and tested for biological activity. Stimulates the caspase-1 activating NLRP3/NALP3 inflammasome, resulting in the production of active IL-1beta and IL-18. - NLRP3/NALP3 inflammasome activator. Specially crystallized and tested for biological activity. Stimulates the caspase-1 activating NLRP3/NALP3 inflammasome, resulting in the production of active IL-1beta and IL-18.
Safety information: 
MSDS: MSDS
Gout-associated uric acid crystals activate the NALP3 inflammasome: F. Martinon, et al.; Nature 440, 237 (2006) Read more
Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases: M.T. Shio, et al.; PLoS Pathog. 5, e1000559 (2009) Read more
Crystals of monosodium urate monohydrate enhance lipopolysaccharide-induced release of interleukin 1 beta by mononuclear cells through a caspase 1-mediated process: E.J. Giamarellos-Bourboulis, et al.; Ann. Rheum. Dis. 68, 273 (2009) Read more
Monosodium urate crystals in inflammation and immunity: Y. Shi, et al.; Immunol. Rev. 233, 203 (2010) Read more
RIP3-mediated necrotic cell death accelerates systematic inflammation and mortality: L. Meng, et al.; PNAS 112, 11007 (2015) Read more