MSI-1436 [186139-09-3]

MedChem Express

MSI-1436 [186139-09-3]

10

186139-09-3

95%

C37H72N4O5S

685.06

MSI-1436 is a selective, non-competitive inhibitor of the enzyme protein-tyrosine phosphatase 1B (PTP1B), with an IC50 of appr 1 microM, 200-fold preference over TCPTP (IC50, 224 microM).

NCCCNCCCCNCCCN[C@@H]1C[C@@](C[C@@H](O)[C@]2([H])[C@]3([H])CC[C@@]4(C)[C@@]2([H])CC[C@@]4([C@H](C)CC[C@@H](OS(=O)(O)=O)C(C)C)[H])([H])[C@]3(C)CC1

2°C to 8°C,-20°C,-80°C

12352200