NG 52 [212779-48-1]

MedChem Express

NG 52 [212779-48-1]

10

212779-48-1

Research Use Only

99.62%

C16H19ClN6O

346.81

NG 52 is a potent, cell-permeable, selective, ATP-compatible and orally active Cdc28p and Pho85p kinase inhibitor with IC50s of 7 microM and 2 microM, respectively. NG 52 also inhibits the activity of phosphoglycerate kinase 1 (PGK1) with an IC50 of 2.5 microM. NG 52 is inactive against yeast kinases Kin28p, Srb10, and Cak1p.

ClC1=CC(NC2=NC(NCCO)=NC3=C2N=CN3C(C)C)=CC=C1

2°C to 8°C,-20°C,-80°C

12352200