Ilginatinib maleate [1354799-87-3]
HY-19631
CAS Number1354799-87-3
Product group Chemicals
Estimated Purity97.04%
Molecular Weight505.5
Overview
- SupplierMedChem Express
- Product NameIlginatinib maleate [1354799-87-3]
- Delivery Days Customer10
- CAS Number1354799-87-3
- CertificationResearch Use Only
- Estimated Purity97.04%
- Molecular FormulaC25H24FN7O4
- Molecular Weight505.5
- Scientific DescriptionIlginatinib maleate (NS-018 maleate) is a highly active and orally bioavailable JAK2 inhibitor, with an IC50 of 0.72 nM, 46-, 54-, and 31-fold selectivity for JAK2 over JAK1 (IC50, 33 nM), JAK3 (IC50, 39 nM), and Tyk2 (IC50, 22 nM).
- SMILESCN1N=CC(C2=CC(N[C@H](C3=CC=C(F)C=C3)C)=NC(NC4=NC=CN=C4)=C2)=C1.O=C(O)/C=C\C(O)=O
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200