Oxidopamine hydrochloride [28094-15-7]

MedChem Express

Oxidopamine hydrochloride [28094-15-7]

10

28094-15-7

Research Use Only

98%

C8H12ClNO3

205.64

Oxidopamine (6-OHDA) hydrochloride is an antagonist of the neurotransmitter dopamine. Oxidopamine hydrochloride is a widely used neurotoxin and selectively destroys dopaminergic neurons. Oxidopamine hydrochloride promotes COX-2 activation, leading to PGE2 synthesis and pro-inflammatory cytokine IL-1beta secretion. Oxidopamine hydrochloride can be used for the research of Parkinsons disease (PD), attention-deficit hyperactivity disorder (ADHD), and Lesch-Nyhan syndrome.

OC1=CC(CCN)=C(O)C=C1O.[H]Cl

2°C to 8°C

12352200