PAP-1 [870653-45-5]
HY-10015
CAS Number870653-45-5
Product group Chemicals
Estimated Purity99.16%
Molecular Weight350.36
Overview
- SupplierMedChem Express
- Product NamePAP-1 [870653-45-5]
- Delivery Days Customer10
- CAS Number870653-45-5
- CertificationResearch Use Only
- Estimated Purity99.16%
- Molecular FormulaC21H18O5
- Molecular Weight350.36
- Scientific DescriptionPAP-1 (5-(4-Phenoxybutoxy)psoralen) is a potent, selective, and orally active Kv1.3 blocker (EC50=2 nM). PAP-1 blocks Kv1.3 in a use-dependent manner and acts by preferentially binding to the C-type inactivated state of the channel. PAP-1 exhibits 23-fold selectivity over Kv1.5 (EC50=45 nM), and further displays 33- to 125-fold selectivity over all other Kv1-family channels. PAP-1 does not exhibit cytotoxic or phototoxic effects.
- SMILESO=C1C=CC(C(O1)=CC2=C3C=CO2)=C3OCCCCOC4=CC=CC=C4
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200